1. Catalytic Transfer Functionalization through Shuttle Catalysis
Bhawal, Benjamin N., Bill Morandi. ACS Catalysis, 2016,

2. 1. Shuttle Catalysis Concept
2. Selected Examples of Shuttle Catalysis Reactions
3. Summary

3. 1. Shuttle Catalysis Concept2.
1. Shuttle Catalysis Concept 2.
Scheme 1. Transfer Hydrogenation
1. Wang, Dong, Didier Astruc. Chemical reviews , 2015,

4. Scheme 2. Generalization of the Shuttle Catalysis Concept
Scheme 3. Definition of Forward and Reverse Shuttle Catalysis Reactions

5. 2. Selected Examples of Shuttle Catalysis Reactions
Scheme 4. Metal−Organic Cooperatively Catalyzed
Hydroacylation of Alkenes by Transfer of an Aldehyde
2. Jun, C.-H.; Lee, H. J. Am. Chem. Soc. 1999, 121, 880−881.

6. Scheme 5. Rhodium-Catalyzed Retro-hydroformylation of Aldehydes
3. Murphy, S. K.; Park, J.-W.; Cruz, F. A.; Dong, V. M. Science. 2015, 347, 56−60.

7. Scheme 6. Alkene Transfer Hydrocyanation, the Forward Process
4. Fang, X.; Yu, P.; Morandi, B. Science 2016, 351, 832−836.

8. Scheme 7. Retro-hydrocyanation, the Reverse Process
5. Lo, J. C.; Yabe, Y.; Baran, P. S. J. Am. Chem. Soc. 2014, 136, 1304−1307.

9. Scheme 8. Catalytic Transfer Hydromagnesiation
6. Shirakawa, E.; Ikeda, D.; Masui, S.; Yoshida, M.; Hayashi, T. J. Am. Chem. Soc. 2012, 134, 272−279.6.

10. Scheme 9. Catalytic Transfer Silacyclopropanation
7. Driver, T. G.; Woerpel, K. A. J. Am. Chem. Soc. 2003, 125, 10659−10663.

11. 1. 金属催化的反应
2. 涉及烯烃作为受体或者供体，官能化或者去官能化
3. 可逆的反应过程，需要一定的驱动力