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Lab 5- ALS, Trigeminal System
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ALS
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Note Cell body locations:
ALS AN OVERVIEW OF THE ANTEROLATERAL SYSTEM FOR PAIN AND TEMPERATURE SENSATION Note Cell body locations: Primary sensory afferent cell bodies DRG all levels of the spinal cord Fast fibers – Ad fibers intense sharp pain Slow Fibers – C fibers dull throbbing, burning pain Primary Central Processes enter via lateral aspect of dorsal roots Ventral white commisure
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Haines 5-1 Lamina 1+5 = projection neurons pain and temp.
Lissauers tract in dorsal horn Lamina 2+3 = Substantia gelatinosa -receives afferents ALS Ventral White Commisure Sacral Level
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Haines 5-2 Lissauers tract in dorsal horn
Lamina 1+5 = projection neurons pain and temp. Lamina 2+3 = Substantia gelatinosa -receives afferents ALS Ventral White Commisure Lumbar Level
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Haines 5-3 Lamina 5 = projection neurons pain and temp.
Lissauers tract in dorsal horn Lamina 1+2 ALS Ventral White Commisure Thoracic Level
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Haines 5-4 Lamina 5 = projection neurons pain and temp.
Lissauers tract in dorsal horn Lamina 2 Substantia gelatinosa -receives afferents ALS Ventral White Commisure C7 Level
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Haines 5-5 Lamina 5 = projection neurons pain and temp.
Lissauers tract in dorsal horn Substantia gelatinosa -receives afferents ALS Ventral White Commisure C1 Level
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Haines 5-9 Tegmentum = Reticular Formation + Periventricular Zone
Keep in Mind that the reticular formation is a poorly defined area. ALS Fast Fibers Caudal Medulla Level
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Haines 5-11 ALS Midrostral Medulla Level
Reticular Formation – receives slow ALS fibers that take Multisynaptic course Haines 5-11 ALS Fast fiber Midrostral Medulla Level
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Haines 5-12 ALS Rostral Medulla Level
Reticular Formation – receives slow ALS fibers that take Multisynaptic course ALS Fast fiber Rostral Medulla Level Raphe Nucleus – Decending Pain Block (Serotonin or NorEp)
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Haines 5-17 ALS Rostral Medulla Level
Reticular Formation – receives slow ALS fibers that take Multisynaptic course ALS Fast fiber Rostral Medulla Level Raphe Nucleus – Decending Pain Block (Serotonin or NorEp)
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Haines 5-19 ALS Rostral Pons Level
Reticular Formation – receives slow ALS fibers that take Multisynaptic course Haines 5-19 ALS Fast fiber Rostral Pons Level Raphe Nucleus – Decending Pain Block (Serotonin or NorEp)
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Haines 5-20 ALS Rostral Pons Level
Reticular Formation – receives slow ALS fibers that take Multisynaptic course ALS Fast fibers Medial Lemniscus Rostral Pons Level
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Haines 5-22 Reticular Formation – receives slow ALS fibers that take Multisynaptic course Periaqueductal Gray – receives fibers from ALS, and sends decending fibers to the Raphe Nucleus ALS Fast fibers Pons/midbrain jctn Level
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Periaqueductal Gray – receives fibers from ALS, and sends decending fibers to the Raphe Nucleus
Haines 5-25 Reticular Formation – receives slow ALS fibers that take Multisynaptic course ALS Fast Fibers Rostral Midbrain Level
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Haines 5-30 Contains fibers from both: ALS and Medial Lemniscus
Thalmus
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Haines 5-31 Slow Tract Receives pain and temp fibers from reticular formation and sends axons to different areas of the cortex.
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Black Board 28
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Black Board 29
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Black Board 30
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Black Board 31
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Black Board 33 Posterior limb of internal capsule
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Trigeminal System
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Tigeminal System (CN5) (1) (2) (3) VTTT Trigeminal nuclear Complex
unconscious proprioceptors (2) Note: Fibers cross the midline Trigeminal nuclear Complex (3)
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Haines 5-8 Spinaltrigeminal Nucleus
Spinaltrigeminal tract – ipsilateral pain and temp from face and teeth Caudal Medulla
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Haines 5-9 Spinaltrigeminal Nucleus – sends axons that cross at accend to VPM Spinaltrigeminal tract – ipsilateral pain and temp from face and teeth Caudal Medulla Level
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Axons cross and ascend in to VTTT at the caudal pons and continue to the VPM
Haines 5-11 Spinaltrigeminal Nucleus Spinaltrigeminal tract – ipsilateral pain and temp from face and teeth Midrostral Medulla Level
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Haines 5-12 Spinaltrigeminal Nucleus Spinaltrigeminal tract
Rostral Medulla Level
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Haines 5-17 Spinaltrigeminal Nucleus Spinaltrigeminal tract
Rostral Medulla Level
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Haines 5-19 Main Motor Nucleus Trigeminal Roots Main Sensory Nucleus
Supplies muscles of mastication Trigeminal Roots Main Sensory Nucleus Discriminative touch Receives fibes from trigem ganglion Sends axons across midline to VTTT Mixed VTTT Contralateral spinotrgeminal tract (Ipsilateral) Rostral Pons Level
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Haines 5-25 VTTT Contralateral Rostral Midbrain Level
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Haines 5-30 VPM = sensory relay nucleus for general face sensation and for taste Posteror Limb of Internal Capsule Thalmus
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Haines 2-11
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