1. EPRUMA – Part of Responsible Use Declan O’ Brien on behalf of EPRUMA TAIEX, Istanbul, April 19th, 2011

2. Why EPRUMA?
The motivation behind launching EPRUMA was to build stakeholder agreement on what constitutes “Responsible Use” of veterinary medicines
We have very good agreement & collaboration across European stakeholders:
COPA-COGECA (farmers & co-operatives), EISA (European Initiative for Sustainable Development in Agriculture), FECAVA (small animal vets), FEFAC (feed manufacturers), FESASS (animal-health farmer organisations), FVE (veterinary surgeons) & IFAH-Europe (animal health industry), PGEU (pharmacists)
All pre-farm gate stakeholders support EPRUMA
We actively welcome new members

3. EPRUMA partners:

4. Objectives of EPRUMA
Promote animal health & welfare as well as human health through the “Responsible Use” of veterinary medicines
an essential component of public health
Develop “best practice” frameworks concerning the use of veterinary medicines
Communicate with & involve all parties concerned with the “Responsible Use” of veterinary medicines 4

5. “Responsible Use” of Veterinary Medicines
Bio-security: preventative measures aimed at keeping diseases out of groups of animals or to limit the spread of disease within an animal population
Good housing
Appropriate nutrition
Regular monitoring of health and welfare
Herd health plans: tailored to record specific actions for individual farms
Vaccination
Diagnosis and treatment under veterinary care
Use medicines according to instructions 5

6. Policy Context Medicated Feed legislation being reviewed
Veterinary Directive being reviewed
Commission ‘Staff Working Paper’ consultation
CVMP consultation
Heads of Medicines Agencies consultation
EU/US dialogue
Innovation being promoted – Europe 2020

7. Communication Activities
Website launched during Vet Week in June, 2010
Antimicrobial framework translated into Czech, Dutch, English, French, German, Hungarian, Italian, Polish, Romanian, Turkish & Spanish!
EPRUMA present at relevant conferences – e.g. Vet Week, Congress of European Farmers
Plan to present to veterinary students across Universities
Plan to include in Continuous Professional Development courses for practicing veterinarians
Leaflet & ‘roll up’ developed & Poster being developed 7

8. 8

9. Vet Week, June, 2010 9

10. Additional Antimicrobial Initiatives
EPRUMA welcomes the EMA initiative on collecting volume information across the EU
Important information that has not been available to date
Ongoing reports from EFSA provide additional valuable information
Need to also present Clinical breakpoint data
EU/US Dialogue ongoing
Animal Health Law & “One Health” 10

11. Implementation in the Field
Met with Commissioner Dalli in September, 2010
Need to communicate
Provide information to those who make the decisions especially veterinarians
Continuous Professional Development as route 11

12. Industry Recommendations - 1
We should use all existing & new classes strategically – possibly in rotation & guided by diagnostics - to minimise resistance development to all classes
We can protect the efficacy of existing & new antibiotics via ongoing diagnostics – use to inform future antimicrobial choices
We promote the idea of significantly restricting the ‘cascade’ as a means of combating resistance – cascade by ‘exceptional exception’ but critical to have the cascade

13. Industry Recommendations - 2
We propose extended data protection for new molecules to ensure innovation continues
With a combination of diagnostics, restrictions on off label use, appropriate use of new molecules & classes coupled with extended data protection, concerns of most stakeholders have been addressed

14. Conclusions
EPRUMA has established very constructive collaboration across stakeholders
EPRUMA has been very active in promoting “Responsible Use”
Our activities complement European policy & legislation
We need support to communicate “Responsible Use” and to really make a difference on the ground
Strategic use of all classes supported by diagnostics can protect long term efficacy
Restrict use of ‘cascade’ but critical to have it
Stimulate innovation
EPRUMA is a critical part of an overall policy to protect the long term efficacy of antimicrobials 14