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IgM Anti-Ganglioside Antibodies Induced by Melanoma Cell Vaccine Correlate with Survival of Melanoma Patients Takenori Takahashi, Timothy D. Johnson, Yumiko Nishinaka, Donald L. Morton, Reiko F. Irie Journal of Investigative Dermatology Volume 112, Issue 2, Pages (February 1999) DOI: /j x Copyright © 1999 The Society for Investigative Dermatology, Inc Terms and Conditions
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Figure 1 IgM anti-ganglioside antibodies by ELISA in sera of melanoma patients at weeks 0 and 4. All sera were tested at 1:200 dilution. The statistical differences in these results are tabulated in Table 1 . Journal of Investigative Dermatology , DOI: ( /j x) Copyright © 1999 The Society for Investigative Dermatology, Inc Terms and Conditions
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Figure 2 Percentage of patients whose sera displayed an OD value higher than the cut-off OD value. The cut-off OD value was determined by taking the upper 95% confidence value for the 1 y survival group. The cut-off values were for anti-GD2, for anti-GM2, for anti-GM3, and for anti-GD3. □, 5 y group; , 2–5 y group;▪, 1 y group. The p value from a test of the odds ratio compares the percentage of high responders in 5 y and 2–5 y groups with that in the 1 y group. Journal of Investigative Dermatology , DOI: ( /j x) Copyright © 1999 The Society for Investigative Dermatology, Inc Terms and Conditions
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