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Basics of Immunotherapy Potential Therapeutic Targets.

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Presentation on theme: "Basics of Immunotherapy Potential Therapeutic Targets."— Presentation transcript:

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4 Basics of Immunotherapy

5 Potential Therapeutic Targets

6 Common Checkpoint Molecules in Immunotherapy

7 Nivolumab

8 Pembrolizumab

9 Toxicity With Checkpoint Inhibitors

10 Key Points Regarding Toxicity

11 Considerations for Toxicity Management

12 Completed Studies With First-Line Checkpoint Inhibitors

13 First-Line Anti-PD-L1: Durvalumab

14 CheckMate 012 Efficacy Results

15 CheckMate 012 Safety Results

16 CheckMate 568

17 KEYNOTE-021 Design

18 KEYNOTE-021 Efficacy Results

19 KEYNOTE-021 Safety Results

20 Other Treatment Considerations

21 POPLAR Study Outcomes

22 Additional Combination Studies

23 PD-L1 Testing

24 IFNγ as a Biomarker in Durvalumab in NSCLC

25 Additional Second-Line Checkpoint Inhibitor Combination Studies

26 Concluding Remarks

27 Abbreviations

28 Abbreviations


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