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Sefika Canan Mizrak, Federica M.F. van Dissel-Emiliani 

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Presentation on theme: "Sefika Canan Mizrak, Federica M.F. van Dissel-Emiliani "— Presentation transcript:

1 Transient receptor potential vanilloid receptor-1 confers heat resistance to male germ cells 
Sefika Canan Mizrak, Federica M.F. van Dissel-Emiliani  Fertility and Sterility  Volume 90, Issue 4, Pages (October 2008) DOI: /j.fertnstert Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Photomicrographs of sections through mice testes (A, B, C57BL/6, WT; C, D, C57BL/6-B6.129S4-Vr1tm1Jul, TRPV1–/–) heated during 15 minutes at 43°C and processed a week later. (A, C) Periodic acid-Schiff–hematoxylin staining. (B, D) TUNEL labeling. Brown cells, TUNEL (+) germ cells. Note the number of apoptotic germ cells in the WT testis (diaminobenzidine precipitate) and the lack of these cells in the TRPV1–/– testis. (E) C57BL/6,WT and (F) C57BL/6-B6.129S4-Vr1tm1Jul, TRPV1–/– mice testes heated during 15 minutes at 33°C and processed a week later; both E and F show PAS-hematoxylin staining. Bars, 100 μm. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions


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