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Steatosis Is a Cofactor in Liver Injury in Hemochromatosis

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Presentation on theme: "Steatosis Is a Cofactor in Liver Injury in Hemochromatosis"— Presentation transcript:

1 Steatosis Is a Cofactor in Liver Injury in Hemochromatosis
Elizabeth E. Powell, Azmat Ali, Andrew D. Clouston, Jeannette L. Dixon, Douglas J. Lincoln, David M. Purdie, Linda M. Fletcher, Lawrie W. Powell, Julie R. Jonsson  Gastroenterology  Volume 129, Issue 6, Pages (December 2005) DOI: /j.gastro Copyright © 2005 American Gastroenterological Association Terms and Conditions

2 Figure 1 In C282Y homozygous patients, grade of steatosis increases with increasing body mass index (BMI). *P < .05, ***P < .001 compared with BMI <25. (Kruskal–Wallis test). Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2005 American Gastroenterological Association Terms and Conditions

3 Figure 2 In C282Y homozygous patients who are light drinkers (males <30 g/day; females <10 g/day) or moderate to heavy drinkers (males ≥30 g/day; females ≥10 g/day), the percentage of patients with steatosis on biopsy is increased in obese (BMI ≥30) patients. **P < .01 compared with lean (BMI <25) and overweight patients (BMI 25–29.9) for light drinkers. **P < .01 compared with lean patients for moderate to heavy drinkers. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2005 American Gastroenterological Association Terms and Conditions


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