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Acute localized exanthematous pustulosis (ALEP) caused by lamotrigine

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1 Acute localized exanthematous pustulosis (ALEP) caused by lamotrigine
Zachary Hopkins, BS, Alice Frigerio, MD, PhD, Jennie T. Clarke, MD  JAAD Case Reports  Volume 4, Issue 7, Pages (August 2018) DOI: /j.jdcr Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 A, ALEP; initial rash presentation consisted of pustules and vesicles on a base of erythema and edema, predominantly on the right side of the face. B, Punch biopsy from the right cheek showed spongiosis and subcorneal pustules with neutrophils. (Hematoxylin-eosin stain; original magnification: ×200.) The presentation was consistent with ALEP. JAAD Case Reports 2018 4, DOI: ( /j.jdcr ) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 A, AGEP; the rash recurred upon rechallenge with lamotrigine. B, Lesions were now widespread and consistent with AGEP. JAAD Case Reports 2018 4, DOI: ( /j.jdcr ) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions


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