1. Anxiety and Decision Making
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Anxiety and Decision Making

3. About 3-5 years…

4. Ask Questions when you need to…

5. Anxiety Broad definition in the DSM-IV
300.02 Generalized anxiety disorder
Panic disorder
With agoraphobia
Without agoraphobia
300.22 Agoraphobia without history of panic disorder
300.29 Specific phobia
300.23 Social phobia
300.3 Obsessive-compulsive disorder
309.81 Posttraumatic stress disorder
308.3 Acute stress disorder
Anxiety disorder
Anxiety disorder due to a general medical condition
Anxiety disorder due to... [indicate the general medical condition]
Anxiety disorder NOS

6. Generalized Anxiety Disorder
6 months of worry
Difficulty controlling anxiety
3 months of 3 or more:
Feeling tense
Fatigue easily
Can’t concentrate
Irritable
Significant muscle tension
Sleep difficulty
Symptoms not related to another mental disorder
“Clinical significant distress”, ↓ daily life fxn
Not due to substance or medical issue

7. Yerkes-Dodson law
Anxiety or Stress

8. Animal tests for Anxiety
Open field test
Novelty suppressed feeding
Elevated platform
Elevated plus maze
Social Interaction Test
Others…

9. Decision making
Choice
Stress-Choice Model
Y-Maze
Straight alley maze

10. Decisions Decisions Fight or flight Save for the future
Limbic System: Amygdala, hippocampus, etc
Save for the future
Prefrontal cortex, cortex others…

11. For this class Presentation article: Background papers Original work
Animal models
Neuroscience based
Background papers
fMRI (humans)
Review articles
Help tie the story together

12. Thank you