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Antimicrobial Activity of SCH 27899, Oligosaccharide Member of the Everninomycin Class with a Wide Gram-Positive Spectrum  Ronald N. Jones, M.D., Mary.

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Presentation on theme: "Antimicrobial Activity of SCH 27899, Oligosaccharide Member of the Everninomycin Class with a Wide Gram-Positive Spectrum  Ronald N. Jones, M.D., Mary."— Presentation transcript:

1 Antimicrobial Activity of SCH 27899, Oligosaccharide Member of the Everninomycin Class with a Wide Gram-Positive Spectrum  Ronald N. Jones, M.D., Mary S. Barrett, B.S.  Clinical Microbiology and Infection  Volume 1, Issue 1, Pages (September 1995) DOI: /j tb00022.x Copyright © 1995 European Society of Clinical Infectious Diseases Terms and Conditions

2 Figure 1 Structure of SCH 27899.
Clinical Microbiology and Infection 1995 1, 35-43DOI: ( /j tb00022.x) Copyright © 1995 European Society of Clinical Infectious Diseases Terms and Conditions

3 Figure 2 Kill curve for S. aureus ATCC at everninomycin base concentrations of 0.5 μg/ml (MIC), 1 μg/ml (two-fold the MIC), and 4 μg/ml (eight-fold the MIC). Clinical Microbiology and Infection 1995 1, 35-43DOI: ( /j tb00022.x) Copyright © 1995 European Society of Clinical Infectious Diseases Terms and Conditions

4 Figure 3 Kill curve for a total of four gram-positive cocci tested at 4 μg/ml everninomycin base (eight- to 16-fold the MIC). MR = methicillin-resistant and MS = methicillin-susceptible (MIC 8 ≤ μg/ml). Clinical Microbiology and Infection 1995 1, 35-43DOI: ( /j tb00022.x) Copyright © 1995 European Society of Clinical Infectious Diseases Terms and Conditions


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