1. Improving CABG Surgery
Amir Durrani
Ben Hoagland
Santosh Tumkur
Lucas Burton
Advisor: Thomas P. Ryan, Ph.D.

2. Project Goals Improve harvested vessel attachment
Design device to aid in grafting
Reduce suturing difficulty
Improve local stabilization

3. Overview of Off-Pump CABG
Coronary Artery Bypass Graft
Procedure to introduce increased blood flow to occluded coronary arteries
Harvested vessels grafted to coronary arteries

4. Market Potential
150,000 Off-pump CABG surgeries performed worldwide each year
Charge for a CABG procedure ranges from $37,000 and $72,000 per case
$26 Billion spent per year on CABG surgeries
Use of beating heart techniques has grown more than 40% each year since 1997

5. Problems Stabilization is required to perform CABG on a beating heart
Effective vessel-artery contact is imperative
Complex suturing techniques required
Current stabilizers don’t provide adequate local stabilization of graft site
Heart positioning problems
Heart hemodynamics

6. Possible Solution 1 Y-joint grafting device Shunt-like
External harvested vessel attachment
Intra-vascular component
Absorbable
Biocompatible
Beveled attachment point

7. Possible Solution 2 “Umbrella” grafting device
Circular surface is inserted into coronary artery and adheres to inner vessel surface
Provides a stable vessel connection to facilitate suturing

8. Progress Made
Redirected project toward efficient suturing techniques with improved stabilization
Obtained feedback from biomaterials experts
Utilized Innovation Workbench
Built crude models

9. Current Status Using Ratner as biomaterial reference
Seeking feedback from Dr.’s Greelish and Merrill regarding models
Acquired access to Dr. Jansen’s lab and storage facility
Narrowing solution options

10. Future Plans Develop prototypes
Continue researching possible solutions
Continue consultation with surgeons and engineers for feedback
Test scaled down prototypes on dog and pig hearts
Alter design based on feedback and prototype test results