1. Leukemogenic Activity of Cohesin Rings True
Mark S. Williams, Tim C.P. Somervaille 
Cell Stem Cell 
Volume 17, Issue 6, Pages (December 2015)
DOI: /j.stem
Copyright © 2015 Elsevier Inc. Terms and Conditions

2. Figure 1 Cohesin Complex Mutations in Acute Myeloid Leukemia
The cartoon illustrates the structure of the cohesin complex. For each component, the percentage of AML cases carrying mutations in its gene is indicated in brackets, together with the approximate proportion of truncating versus missense mutations collated from five separate studies (Cancer Genome Atlas Research Network, 2013; Kon et al., 2013; Kihara et al., 2014; Thol et al., 2014; Thota et al., 2014; n = 1,393 individuals). For ease of display, nonsense, frameshift, and splice site mutations are grouped as “truncating” mutations, and missense and inframe indels are grouped as “missense” mutations.
Cell Stem Cell  , DOI: ( /j.stem )
Copyright © 2015 Elsevier Inc. Terms and Conditions