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Risk of sudden unexplained death after use of dihydroartemisinin–piperaquine for malaria: a systematic review and Bayesian meta-analysis  Xin Hui S Chan,

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Presentation on theme: "Risk of sudden unexplained death after use of dihydroartemisinin–piperaquine for malaria: a systematic review and Bayesian meta-analysis  Xin Hui S Chan,"— Presentation transcript:

1 Risk of sudden unexplained death after use of dihydroartemisinin–piperaquine for malaria: a systematic review and Bayesian meta-analysis  Xin Hui S Chan, MRCP, Yan Naung Win, MPH, Laura J Mawer, MBBChir, Jireh Y Tan, MS, Prof Josep Brugada, PhD, Prof Nicholas J White, FRS  The Lancet Infectious Diseases  Volume 18, Issue 8, Pages (August 2018) DOI: /S (18) Copyright © 2018 World Health Organization Terms and Conditions

2 Figure 1 Study selection
DP=dihydroartemisinin–piperaquine. MSAT=mass screen and treat. IPT=intermittent preventive therapy. IST=intermittent screen and treat. SMC=seasonal malaria chemoprevention. PK=pharmacokinetic. The Lancet Infectious Diseases  , DOI: ( /S (18) ) Copyright © 2018 World Health Organization Terms and Conditions

3 Figure 2 Number of individuals exposed to, and deaths after, dihydroartemisinin–piperaquine The Lancet Infectious Diseases  , DOI: ( /S (18) ) Copyright © 2018 World Health Organization Terms and Conditions

4 Figure 3 Causes of death after dihydroartemisinin–piperaquine
Data presented by age group and treatment indication. The Lancet Infectious Diseases  , DOI: ( /S (18) ) Copyright © 2018 World Health Organization Terms and Conditions


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