1. Real-World Safety of NOACs: What Do We Know Today?

2. Program Goals

3. NOACs: A Revolution in the Management of Thrombotic Disorders

4. Clinical Trials Vs Real World Evidence (RWE)

5. Spectrum of Real World Trials

6. Strengths and Weaknesses of Real World Trials

7. XANTUS: A Prospective Registry

8. XANTUS

9. Recently Published Claims Databases*

10. Recently Published Claims Database Analyses of Rivaroxaban vs VKA for NVAF and Comparison of Results to ROCKET AF

11. Recently Published Claims Database Analyses of Apixaban vs VKA for NVAF and Comparison of Results to ARISTOTLE

12. Recently Published Claims Database Analyses of Dabigatran Vs VKA for NVAF and Comparison of Results to RE-LY

13. Claims Database NOACs

14. XALIA A Prospective, Non-Interventional Study

15. XALIA: Propensity Score Adjustment

16. Treatment-Emergent Clinical Outcomes (Propensity-Score Adjusted Comparison)

17. EINSTEIN CHOICE Study Design

18. EINSTEIN CHOICE: Primary Outcome Recurrent VTE

19. EINSTEIN CHOICE: Bleeding Outcomes

20. Concluding Remarks

21. Abbreviations