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The Architects of B and T Cell Immune Responses

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Presentation on theme: "The Architects of B and T Cell Immune Responses"— Presentation transcript:

1 The Architects of B and T Cell Immune Responses
Peter J.L. Lane  Immunity  Volume 29, Issue 2, Pages (August 2008) DOI: /j.immuni Copyright © 2008 Elsevier Inc. Terms and Conditions

2 Figure 1 LTi Maintain Microenvironments for T and B Cell Responses through Expression of Diverse TNF-Ligands The top panel shows T cell-independent ILFs. The middle panel shows CD4+ T cell help to B cells in ILFs. The bottom panel shows classical TD responses. In B follicles, T cells and FDCs foster AID-dependent GC affinity maturation. In the outer T zone, T cells and DCs foster AID-dependent class switching in B cells that become plasma cells. Immunity  , DOI: ( /j.immuni ) Copyright © 2008 Elsevier Inc. Terms and Conditions


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