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Rhodococcus equi Virulence-Associated Antigens and Specific Antibody Response in AIDS Patients Infected with R. equi  Claudio Maria Mastroianni, M.D.,

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Presentation on theme: "Rhodococcus equi Virulence-Associated Antigens and Specific Antibody Response in AIDS Patients Infected with R. equi  Claudio Maria Mastroianni, M.D.,"— Presentation transcript:

1 Rhodococcus equi Virulence-Associated Antigens and Specific Antibody Response in AIDS Patients Infected with R. equi  Claudio Maria Mastroianni, M.D., Miriam Lichtner, M.D., Fabio Mengoni, B.Sc., Maria Teresa Mascellino, B.Sc., Vincenzo Vullo, M.D., Salvatore Delia, M.D.  Clinical Microbiology and Infection  Volume 1, Issue 1, Pages (September 1995) DOI: /j tb00019.x Copyright © 1995 European Society of Clinical Infectious Diseases Terms and Conditions

2 Figure 1 lmmunoblot (A) and plasmid (8)p rofiles of R. eqoistrains. The virulence-associated 15- to 17-kDa antigens were detected by immunoblotting with naturally infected foal serum. Plasmid DNA was isolated, analyzed on a 0.8% agarose gel, and stained with ethidium bromide. Lanes: 1, strain 56830; 2, strain 212B; 3, strain 239D; 4, strain 22758; 5, strain 2633C; 6, strain 210D; 7, strain 6058; 8, strain ATCC Arrow at right indicates band for 15- to 17-kOa antigens. Abbreviations: pl=85-kb plasmid; chr=chromosomal DNA. Clinical Microbiology and Infection 1995 1, 18-23DOI: ( /j tb00019.x) Copyright © 1995 European Society of Clinical Infectious Diseases Terms and Conditions

3 Figure 2 lmmunoblot analysis of serological antibody response to R. equi in AIDS patients infected with avirulent (lanes 1-6) and virulent R. equi(lane 7). The ATCC reference strain was used for the preparation of whole-cell antigens. Lanes 1, 2, 4 and 5: recovered patients; lane 6: patient with asymptomatic R. equi infection; lanes 3 and 7: patients who died from R. equi pneumonia. Numbers at right indicate molecular mass Clinical Microbiology and Infection 1995 1, 18-23DOI: ( /j tb00019.x) Copyright © 1995 European Society of Clinical Infectious Diseases Terms and Conditions


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