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Representative radio-HPLC chromatograms for individual pooled methanolic fecal extracts for periods of maximum recovery of radioactivity after dosing of healthy male subjects with a single 400-mg oral dose of [14C]darunavir either alone (A) or with ritonavir (100 mg b.i.d.) (B). Representative radio-HPLC chromatograms for individual pooled methanolic fecal extracts for periods of maximum recovery of radioactivity after dosing of healthy male subjects with a single 400-mg oral dose of [14C]darunavir either alone (A) or with ritonavir (100 mg b.i.d.) (B). Marc Vermeir et al. Drug Metab Dispos 2009;37: The American Society for Pharmacology and Experimental Therapeutics
![Representative radio-HPLC chromatograms for individual pooled methanolic fecal extracts for periods of maximum recovery of radioactivity after dosing of healthy male subjects with a single 400-mg oral dose of [14C]darunavir either alone (A) or with ritonavir (100 mg b.i.d.) (B).](http://slideplayer.com./slide/15019089/91/images/1/Representative+radio-HPLC+chromatograms+for+individual+pooled+methanolic+fecal+extracts+for+periods+of+maximum+recovery+of+radioactivity+after+dosing+of+healthy+male+subjects+with+a+single+400-mg+oral+dose+of+%5B14C%5Ddarunavir+either+alone+%28A%29+or+with+ritonavir+%28100+mg+b.i.d.%29+%28B%29..jpg "Representative radio-HPLC chromatograms for individual pooled methanolic fecal extracts for periods of maximum recovery of radioactivity after dosing of healthy male subjects with a single 400-mg oral dose of [14C]darunavir either alone (A) or with ritonavir (100 mg b.i.d.) (B). Marc Vermeir et al. Drug Metab Dispos 2009;37: The American Society for Pharmacology and Experimental Therapeutics.")
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