1. Regulation of Homeostasis and Inflammation in the Intestine
Thomas T. MacDonald, Ivan Monteleone, Massimo Claudio Fantini, Giovanni Monteleone 
Gastroenterology 
Volume 140, Issue 6, Pages (May 2011)
DOI: /j.gastro
Copyright © 2011 AGA Institute Terms and Conditions

2. Figure 1
Distribution of T cells and accessory cells in the normal human colon. CD68, the gold-standard tissue macrophage marker, identifies a population of cells predominantly below the epithelium. Major histocompatibility complex (MHC) class II, however, identifies a much larger population of cells, including subepithelial macrophages, but also populations of cells deeper in the lamina propria, which are probably DCs. T cells identified by anti-CD3 staining are sparse. Immunoperoxidase immunohistochemistry, original magnification ×100.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2011 AGA Institute Terms and Conditions

3. Figure 2
DCs can activate distinct subsets of Th cells in the gastrointestinal tract. CD103-expressing DCs can extend dendrites into the lumen and internalize antigens to promote differentiation of FoxP3-positive Treg cells. TGF-β1 and RA contribute to differentiation of Treg cells. By contrast, CD11b+ DCs can produce IL-12 and IL-23 and promote the differentiation of Th1 and Th17 cells; this process is negatively regulated by Treg cells.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2011 AGA Institute Terms and Conditions

4. Gastroenterology 2011 140, 1768-1775DOI: (10. 1053/j. gastro. 2011. 02
Copyright © 2011 AGA Institute Terms and Conditions

5. Gastroenterology 2011 140, 1768-1775DOI: (10. 1053/j. gastro. 2011. 02
Copyright © 2011 AGA Institute Terms and Conditions

6. Gastroenterology 2011 140, 1768-1775DOI: (10. 1053/j. gastro. 2011. 02
Copyright © 2011 AGA Institute Terms and Conditions

7. Gastroenterology 2011 140, 1768-1775DOI: (10. 1053/j. gastro. 2011. 02
Copyright © 2011 AGA Institute Terms and Conditions