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Volume 130, Issue 2, Pages S132-S137 (February 2006)

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1 Volume 130, Issue 2, Pages S132-S137 (February 2006)
Intestinal Transplantation for Short Bowel Syndrome and Gastrointestinal Failure: Current Consensus, Rewarding Outcomes, and Practical Guidelines  Kareem M. Abu–Elmagd  Gastroenterology  Volume 130, Issue 2, Pages S132-S137 (February 2006) DOI: /j.gastro Copyright © 2006 American Gastroenterological Association Terms and Conditions

2 Figure 1 Kaplan–Maier graft survival curves for the intestinal transplant registry population. Note significant improvement in survival over time. Reprinted with permission from Grant et al.3 Gastroenterology  , S132-S137DOI: ( /j.gastro ) Copyright © 2006 American Gastroenterological Association Terms and Conditions

3 Figure 2 Graft survival rates plotted according to the type of immunosuppressive protocol with special reference to induction or recipient pretreatment therapy: (A) The intestinal transplant registry population. (Reprinted with permission from Grant et al.3) (B) The Pittsburgh population. Gastroenterology  , S132-S137DOI: ( /j.gastro ) Copyright © 2006 American Gastroenterological Association Terms and Conditions

4 Figure 3 The intestinal transplant registry patient survival according to the status at the time of transplantation. Note a significantly higher survival rate for patients who were transplanted while waiting at home. Reprinted with permission from Grant et al.3 Gastroenterology  , S132-S137DOI: ( /j.gastro ) Copyright © 2006 American Gastroenterological Association Terms and Conditions

5 Figure 4 The 3 main different types of intestinal transplantation: (A) isolated intestine, (B) combined liver-intestine, and (C) multivisceral containing the stomach, duodenum, pancreas, small bowel, and liver. The en-bloc transplanted organs are shaded. Note inclusion of the pancreas with the combined liver-intestinal graft for technical and logistic reasons. A jejunostomy tube was placed for early feeding and chimney ileostomy was created for surveillance ileoscopy and guided mucosal biopsies. Gastroenterology  , S132-S137DOI: ( /j.gastro ) Copyright © 2006 American Gastroenterological Association Terms and Conditions

6 Figure 5 Survival curves of 762 HPN patients with benign intestinal diseases and 141 intestinal recipients (thick solid curve) who were transplanted at the University of Pittsburgh Medical Center since July 2001 under the new immunosuppressive protocol. The survival data of the HPN patients were extrapolated from the Oley A.S.P.E.N. Information System (OASIS) as previously reported. Adapted from Howard L, Heaphy L, Fleming C, Lininger L, Steiger E. Four years of North American registry home parenteral nutrition outcome data and their implications for patient management. JPEN J Parenter Enteral Nutr. 1991;15:384–393, with permission from the American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). A.S.P.E.N. does not endorse the use of this material in any form other than its entirety. Gastroenterology  , S132-S137DOI: ( /j.gastro ) Copyright © 2006 American Gastroenterological Association Terms and Conditions


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