Download presentation
Presentation is loading. Please wait.
Published byÊΠρομηθεύς Ερμόλαος Κουβέλης Modified over 6 years ago
1
Effect of long-term intranasal oxytocin on sexual dysfunction in premenopausal and postmenopausal women: a randomized trial Dana A. Muin, M.D., M.Sc., Michael Wolzt, M.D., Ph.D., Rodrig Marculescu, M.D., Ph.D., Safoura Sheikh Rezaei, M.D., Mohamed Salama, M.D., Ph.D., Carola Fuchs, Anton Luger, M.D., Ph.D., Elia Bragagna, M.D., Brigitte Litschauer, M.D., Ph.D., Michaela Bayerle- Eder, M.D., Ph.D. Fertility and Sterility Volume 104, Issue 3, Pages e4 (September 2015) DOI: /j.fertnstert Copyright © 2015 American Society for Reproductive Medicine Terms and Conditions
2
Figure 1 Female Sexual Function Index scores at baseline (mean values of visits 1 and 2), at follow-up (FU) period 1 (mean values of visits 3 and 4: group 1 received placebo; group 2 received oxytocin), and at follow-up (FU) period 2 (mean values of visits 6 and 7: group 1 received oxytocin; group 2 received placebo). The two lines between follow-up periods 1 and 2 represent the crossover. Each bar is marked with the standard error of 2. *P<.01 vs. baseline. Fertility and Sterility , e4DOI: ( /j.fertnstert ) Copyright © 2015 American Society for Reproductive Medicine Terms and Conditions
3
Figure 2 Female Sexual Distress Scale-scores at baseline (mean values of visits 1 and 2), at follow-up (FU) period 1 (mean values of visits 3 and 4: group 1 received placebo; group 2 received oxytocin), and at follow-up (FU) period 2 (mean values of visits 6 and 7: group 1 received oxytocin; group 2 received placebo). Each bar is marked with the standard error of 2. *P<.01 vs. baseline. Fertility and Sterility , e4DOI: ( /j.fertnstert ) Copyright © 2015 American Society for Reproductive Medicine Terms and Conditions
4
Figure 3 Sexual Quality of Life–Female scores of group 1 and 2 at baseline (dotted bars represent mean values of visits 1 and 2), at follow-up (FU) period 1 (second bars represent mean values of visits 3 and 4: group 1 received placebo; group 2 received oxytocin), and at follow-up (FU) period 2 (third bars represent mean values of visits 6 and 7: group 1 received oxytocin; group 2 received placebo). Each bar is marked with the standard error of 2. *P<.01 vs. baseline. Fertility and Sterility , e4DOI: ( /j.fertnstert ) Copyright © 2015 American Society for Reproductive Medicine Terms and Conditions
5
Figure 4 Oxytocin plasma levels at baseline and after 15 and 30 minutes of oxytocin or placebo intranasal administration (pg/mg). Fertility and Sterility , e4DOI: ( /j.fertnstert ) Copyright © 2015 American Society for Reproductive Medicine Terms and Conditions
6
Supplemental Figure 1 Study design and timeline.
Fertility and Sterility , e4DOI: ( /j.fertnstert ) Copyright © 2015 American Society for Reproductive Medicine Terms and Conditions
Similar presentations
© 2025 SlidePlayer.com. Inc.
All rights reserved.