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Post Allo-Transplant Epstein-Bar Virus (EBV) Infection of Donor Engrafted Cells May Mimic Relapse of the Primary Disease (Leukemia/Lymphoma)  Rikin K.

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Presentation on theme: "Post Allo-Transplant Epstein-Bar Virus (EBV) Infection of Donor Engrafted Cells May Mimic Relapse of the Primary Disease (Leukemia/Lymphoma)  Rikin K."— Presentation transcript:

1 Post Allo-Transplant Epstein-Bar Virus (EBV) Infection of Donor Engrafted Cells May Mimic Relapse of the Primary Disease (Leukemia/Lymphoma)  Rikin K. Shah, M.D., Wenyi Luo, MD, PhD, Shibo Li, MD, Zhongxin Yu, M.D., David Crawford, MD, PhD  Biology of Blood and Marrow Transplantation  Volume 22, Issue 3, Pages S175-S176 (March 2016) DOI: /j.bbmt Copyright © Terms and Conditions

2 Fig 1(A)H&E section shows florid follicular hyperplasia (B) FISH using X, Y chromosomal probe of tonsillar tissue is composed mainly of male donor cells (red circles), with rare, difficult to find female receipt cells (green circles) Biology of Blood and Marrow Transplantation  , S175-S176DOI: ( /j.bbmt ) Copyright © Terms and Conditions

3 Fig 2 (A)H&E section shows follicular hyperplasia with paracortical expansion and focal necrosis FISH for Epstein-Barr virus is positive for EBV infection (brown color) Biology of Blood and Marrow Transplantation  , S175-S176DOI: ( /j.bbmt ) Copyright © Terms and Conditions


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