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Further insights into the role of the annexin A5 M2 haplotype as recurrent pregnancy loss factor, assessing timing of miscarriage and partner risk  Frank.

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Presentation on theme: "Further insights into the role of the annexin A5 M2 haplotype as recurrent pregnancy loss factor, assessing timing of miscarriage and partner risk  Frank."— Presentation transcript:

1 Further insights into the role of the annexin A5 M2 haplotype as recurrent pregnancy loss factor, assessing timing of miscarriage and partner risk  Frank Tüttelmann, M.D., Petar Ivanov, M.D., Ph.D., Charlotte Dietzel, Anna Sofroniou, Tsvetomira M. Tsvyatkovska, Regina S. Komsa- Penkova, Ph.D., Arseni Markoff, Ph.D., Peter Wieacker, M.D., Nadja Bogdanova, M.D.  Fertility and Sterility  Volume 100, Issue 5, Pages (November 2013) DOI: /j.fertnstert Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Forrest plots showing odds ratios for M2 carriage in specific RPL groups compared with population controls. An enrichment of M2 carriers is evident in total patient samples (A, odds ratio, 1.6; 95% confidence interval, 1.2–2.1; P=.003) as well as in all subgroups (B, embryonal losses; C, early fetal losses; D, late fetal losses). The highest and significant increase was found for women with early fetal losses (C, odds ratio, 1.9; 95% confidence interval, 1.3–3.0; P=.003). Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions


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