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Strong Evidence That KIAA0319 on Chromosome 6p Is a Susceptibility Gene for Developmental Dyslexia  Natalie Cope, Denise Harold, Gary Hill, Valentina.

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Presentation on theme: "Strong Evidence That KIAA0319 on Chromosome 6p Is a Susceptibility Gene for Developmental Dyslexia  Natalie Cope, Denise Harold, Gary Hill, Valentina."— Presentation transcript:

1 Strong Evidence That KIAA0319 on Chromosome 6p Is a Susceptibility Gene for Developmental Dyslexia 
Natalie Cope, Denise Harold, Gary Hill, Valentina Moskvina, Jim Stevenson, Peter Holmans, Michael J. Owen, Michael C. O’Donovan, Julie Williams  The American Journal of Human Genetics  Volume 76, Issue 4, Pages (April 2005) DOI: /429131 Copyright © 2005 The American Society of Human Genetics Terms and Conditions

2 Figure 1 Flow diagram of the samples used at each stage of the analysis The American Journal of Human Genetics  , DOI: ( /429131) Copyright © 2005 The American Society of Human Genetics Terms and Conditions

3 Figure 2 Location of candidate genes on chromosome 6p. The location of SNPs found to be significant (P≤.05) in our case-control sample are shown relative to nearby markers. The direction of transcription is shown for each gene. LD blocks across the region are based on data from HapMap. The P value refers to the most significant haplotype (2-1) comprising the two SNPs indicated. An asterisk (*) indicates the amino acid–changing SNP in exon 4. The American Journal of Human Genetics  , DOI: ( /429131) Copyright © 2005 The American Society of Human Genetics Terms and Conditions


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