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Published byΣπάρτακος Ζάρκος Modified over 6 years ago
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Flow diagram of the literature search and selection process in the PubMed and Scopus databases.
Flow diagram of the literature search and selection process in the PubMed and Scopus databases. Keywords: “Human epididymis protein 4,” “HE4,” or “WFDC2” were combined with the terms; “gene/tissue/protein expression,” “serum/blood level/concentration,” “bio/tumour marker,” and “cancer/malignancies.” When HE4-expressing tissues or conditions influencing serum HE4 concentration was revealed, the respective terms were used in further literature search. A total of 42 studies published from 2000 to 2014 were included. Nikoline S. Karlsen et al. Cancer Epidemiol Biomarkers Prev 2014;23: ©2014 by American Association for Cancer Research
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