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Volume 14, Issue 5, Pages 685-691 (May 2017)
Long-term outcomes in leadless Micra transcatheter pacemakers with elevated thresholds at implantation: Results from the Micra Transcatheter Pacing System Global Clinical Trial Jonathan P. Piccini, MD, MHS, FHRS, Kurt Stromberg, MS, Kevin P. Jackson, MD, Verla Laager, MA, Gabor Z. Duray, MD, PhD, Mikhael El-Chami, MD, FHRS, Christopher R. Ellis, MD, FHRS, John Hummel, MD, D. Randy Jones, MD, Robert C. Kowal, MD, PhD, FHRS, Calambur Narasimhan, MD, Razali Omar, MD, FHRS, Philippe Ritter, MD, Paul R. Roberts, MD, Kyoko Soejima, MD, PhD, Shu Zhang, MD, FHRS, Dwight Reynolds, MD, FHRS Heart Rhythm Volume 14, Issue 5, Pages (May 2017) DOI: /j.hrthm Copyright © 2017 The Authors Terms and Conditions
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Figure 1 Pacing thresholds for high threshold patients with paired implant and 6-month thresholds by study visit and pacing system. The red line represents pacing threshold at 0.24 ms for 72 Micra patients with an implant pacing threshold of >1.0 V and 6-month threshold measurement. The black line represents pacing threshold at 0.40 ms for 45 Capture patients with an implant pacing threshold of >1.0 V and 6-month threshold measurement. Error bars represent mean ± SD. Asterisk represents values significantly (P < .05) different from the implant value. Heart Rhythm , DOI: ( /j.hrthm ) Copyright © 2017 The Authors Terms and Conditions
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Figure 2 Micra pacing threshold measurements at discharge (A) and 6 months (B) vs implant. Pacing thresholds at prehospital discharge and 6 months compared to implant thresholds for Micra patients with an implant threshold of >1.0 V at 0.24 ms. Values below the diagonal line represent values lower at the follow-up visit relative to implant. Plotting points are scattered to show the distributional density. Heart Rhythm , DOI: ( /j.hrthm ) Copyright © 2017 The Authors Terms and Conditions
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Figure 3 A: Distribution of Micra pacing thresholds at implant according to the number of device deployments. B: Proportion of Micra patients with an implant threshold of ≤1 V vs >1 V at 0.24 ms at implant. The upper and lower bounds of the boxes in panel A represent the 1st and 3rd quartiles; the horizontal black line is the median. The red line connects the mean. The P value is from a linear regression model. In panel B, the odds ratio is the relative increase in the odds of an implant pacing threshold of >1 V per deployment attempt as computed using a logistic regression model. CI = confidence interval. Heart Rhythm , DOI: ( /j.hrthm ) Copyright © 2017 The Authors Terms and Conditions
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Figure 4 Micra capture thresholds at 6-month follow-up according to implant threshold. This figure displays the 6-month follow-up pacing thresholds in the vertical bars according to the baseline pacing capture threshold at implant (on the x-axis). Heart Rhythm , DOI: ( /j.hrthm ) Copyright © 2017 The Authors Terms and Conditions
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