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Targeting TGF-β and the Extracellular Matrix in Marfan's Syndrome

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Presentation on theme: "Targeting TGF-β and the Extracellular Matrix in Marfan's Syndrome"— Presentation transcript:

1 Targeting TGF-β and the Extracellular Matrix in Marfan's Syndrome
Raghu Kalluri, Yuchi Han  Developmental Cell  Volume 15, Issue 1, Pages 1-2 (July 2008) DOI: /j.devcel Copyright © 2008 Elsevier Inc. Terms and Conditions

2 Figure 1 Magnetic Resonance Images of a Normal and a Marfan's Dilated Aortic Root Brooke et al. (2008) suggest that specific AT1 inhibition by losartan blocks TGF-β signaling, preventing deleterious effects that ultimately result in aortic root dilation. The magnetic resonance images were provided by the BIDMC Division of Cardiology. Developmental Cell  , 1-2DOI: ( /j.devcel ) Copyright © 2008 Elsevier Inc. Terms and Conditions

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