1. Projected Project
Find Arabidopsis micro-array data sets related to bacterial pathogenesis and connect them to GO using GenMAPP and MAPPfinder
Become familiar with pathways in Arabidopsis containing gene products affected by bacterial attack/disease; observe where richer GO development on the plant side would be useful
Use Gene Ontology (GO) to create DAGs of gene products of P. syringae pv. tomato DC3000 involved in plant pathogenesis
If possible, inform these with bacterial microarray data imbedded in MAPPfinder

6. Microarray data sets of Arabidopsis challenged by bacterial pathogens currently exist

11. Ultimate goal:
To design an undergraduate teaching exercise that requires students to use the connections between microarray data sets, Gene Ontology, and biological pathways (e.g. using MAPPfinder) to question and explore the roles of particular gene products in a cellular context during disease
Use: (1) breast cancer microarray data (2) bacterial pathogenesis data