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Attention - Class of 2016 Journal Club:

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1 Attention - Class of 2016 Journal Club:
Genomics as a Probe for Disease Biology   Wylie Burke, M.D., Ph.D. N Engl J Med 2003; 349: Monday, , 1.30 pm   This review article from NEJ underlines the importance of genetic research in understanding the pathalogical basis of disease. The article is available from the photocopier in the library or as a .pdf file on the SCM-Class of 2016 site. Regarding DNA mutations you should be able to: Classify different types of mutations (including nonsense, silent, missense and triplet repeat expansion, transitions and transversions) according to their effect on DNA sequence and protein structure Compare loss-of-function and gain-of-function mutations Differentiate between somatic and germ line mutations Differentiate between mutations and polymorphisms  

2 The objectives for the remaining week are as given in the study guide.
This week all sessions except for the journal club on Monday, will be carried out as LGDs/LGISs

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