1. Seizure - European Journal of Epilepsy
The effects of ketogenic diet on the Th17/Treg cells imbalance in patients with intractable childhood epilepsy 
Fen-Fen Ni, Cheng-Rong Li, Jian-Xiang Liao, Guo-Bing Wang, Su-Fang Lin, Yu Xia, Jia-Lun Wen 
Seizure - European Journal of Epilepsy 
Volume 38, Pages (May 2016)
DOI: /j.seizure
Copyright © 2016 British Epilepsy Association Terms and Conditions

2. Fig. 1
Proportion of circulating Th17 and CD4+CD25+Foxp3+ Treg cells in patients with intractable epilepsy. In 14 control patients (Ctrl) and 28 patients with intractable epilepsy before (IE) and after (IE-KD) ketogenic diet, cell populations in peripheral blood were measured by flow cytometry. (A) Proportion of Th17 cells in total CD3+ T cells. (B) Proportion of CD4+CD25+Foxp3+ Tregs. (C) Proportion of Th17 and CD4+CD25+Foxp3+ Tregs cells. Data are shown as mean±SD. Characteristics of the Ctrl and IE-KD populations were compared with IE using one-way ANOVA. *P<.05.
Seizure - European Journal of Epilepsy  , 17-22DOI: ( /j.seizure )
Copyright © 2016 British Epilepsy Association Terms and Conditions

3. Fig. 2
Expression of Th17 transcription factor and Tregs associating factors. In 14 control patients (Ctrl) and 28 patients with intractable epilepsy before (IE) and after (IE-KD) ketogenic diet expression of Th17 transcription factors and Treg-associated factors were measured by real-time PCR, and expressed normalized to GAPDH, an endogenous reference gene. Data are shown as mean±SD. Characteristics of the Ctrl and IE-KD populations were compared with IE using one-way ANOVA. *P<.05.
Seizure - European Journal of Epilepsy  , 17-22DOI: ( /j.seizure )
Copyright © 2016 British Epilepsy Association Terms and Conditions

4. Fig. 3
Expression of mTOR and HIF-1α. In 14 control patients (Ctrl) and 28 patients with intractable epilepsy before (IE) and after (IE-KD) ketogenic diet expression of mTOR and HIF-1α were measured in purified CD4+CD25+ and CD4+CD25− T cells by real-time PCR, and expressed normalized to GAPDH, an endogenous reference gene. Data are shown as mean±SD. Characteristics of the Ctrl and IE-KD populations were compared with IE using one-way ANOVA. *P<.05.
Seizure - European Journal of Epilepsy  , 17-22DOI: ( /j.seizure )
Copyright © 2016 British Epilepsy Association Terms and Conditions

5. Fig. 4
Plasma cytokine IL-17A concentrations in patients with IP. In 14 control patients (Ctrl) and 28 patients with intractable epilepsy before (IE) and after (IE-KD) ketogenic diet plasma cytokine IL-17A concentrations were measured by cytometric bead array assay. Data are shown as mean±SD. Characteristics of the Ctrl and IE-KD populations were compared with IE using one-way ANOVA. *P<.05.
Seizure - European Journal of Epilepsy  , 17-22DOI: ( /j.seizure )
Copyright © 2016 British Epilepsy Association Terms and Conditions