1. Agenda 1/30 FRQ Workshop Case Study Work Case Study Presentations
Overview of Disease and Osmosis
Turn in: worksheet answers and video notes
Homework
1. Water potential video and notes

2. FRQ Strategies

3. Case Study Directions
As a group, read your case study and answer the questions
Then, create a poster presentation that outlines the following:
1. The disease in your case- symptoms, prevalence, treatment
2. How the disease connects to osmosis
3. Draw a picture that shows how the disease disrupts osmosis
4. Explain how the disruption to osmosis causes the symptoms of the disease
5. Describe any treatments/current research
Use keywords like: osmosis, solute, concentration gradient, hypertonic, isotonic, hypotonic in your presentation

4. Cholera and Osmosis The Vibrio cholera bacteria produce a toxin
The toxin binds to the walls of the small intestine and activated cAMP
The activate cAMP cause the CFTR channels to stay open
CFTR channels transport chloride ions out of the cell
Chloride ions rush out of the cell
Now, the outside of the cell is hypertonic (too much solute) so water leaves the cells of the small intestines
This leads to watery diarrhea, a main symptom of cholera

5. Cystic Fibrosis and Osmosis
The faulty CFTR channel doesn’t allow chloride ions to leave the cell
This creates a hypotonic solution outside the cell, so water moves into the lung cells
This means that this mucus outside the lung cells gets very viscous and thick
The CFTR doesn’t allow salt to be reabsorbed, so it can cause salty tasting skin