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Thrombocythemia and polycythemia in patients younger than 20 years at diagnosis: clinical and biologic features, treatment, and long-term outcome by Fiorina Giona, Luciana Teofili, Maria Luisa Moleti, Maurizio Martini, Giovanna Palumbo, Angela Amendola, Maria Gabriella Mazzucconi, Anna Maria Testi, Patrizia Pignoloni, Sonia Maria Orlando, Sara Capodimonti, Mauro Nanni, Giuseppe Leone, Luigi Maria Larocca, and Robin Foà Blood Volume 119(10): March 8, 2012 ©2012 by American Society of Hematology
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Therapeutic algorithm for thrombocythemic and polycythemic children.
Therapeutic algorithm for thrombocythemic and polycythemic children. The graphics in the lowest section show the number of patients undergoing the different therapeutic options: white sections refer to all asymptomatic patients, the gray sections indicate all symptomatic patients, and the darkest sections are indicative of all symptomatic patients resistant to low-dose ASA and/or with uncontrolled myeloproliferation. As a rule, any treatment, including low-dose ASA, is avoided in infants whatever the platelet number. Fiorina Giona et al. Blood 2012;119: ©2012 by American Society of Hematology
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