1. A, baseline and 4-week PET scan from patient 2 (MET c
A, baseline and 4-week PET scan from patient 2 (MET c.3028G>C exon 14 splice variant) following treatment with cabozantinib.
A, baseline and 4-week PET scan from patient 2 (MET c.3028G>C exon 14 splice variant) following treatment with cabozantinib. Imaging shows complete PET response by PERCIST criteria in the patient's liver metastasis. B, baseline and 4-week CT scan from patient 4 (MET c.3024_3028delAGAAGGTATATT exon 14 splice variant) following treatment with crizotinib. Imaging shows a response in the patient's lung tumor. C, baseline and 6-week CT scan from patient 5 (MET c G>T exon 14 splice variant) following treatment with crizotinib. Imaging shows a response in the patient's lung tumor. D, baseline and 6-week CT scan from patient 5 (MET c G>T exon 14 splice variant) following treatment with crizotinib. Imaging shows a response in the patient's liver metastasis. E, baseline and 8-week CT scan from patient 7 (MET c.3028G>T exon 14 splice variant) following treatment with crizotinib. Image shows a response in the patient's lung tumors.
Paul K. Paik et al. Cancer Discov 2015;5:
©2015 by American Association for Cancer Research