1. Induction of tolerance to human factor VIII in mice
by Hengjun Chao, and Christopher E. Walsh
Blood
Volume 97(10):
May 15, 2001
©2001 by American Society of Hematology

2. Level of hFVIII antigen and hFVIII inhibitor titer in C57BL mice (n = 3) after administration of rAAV and BDD-hFVIII.Solid line indicates hFVIII antigen level; and broken line, anti-BDD-hFVIII inhibitor titer.
Level of hFVIII antigen and hFVIII inhibitor titer in C57BL mice (n = 3) after administration of rAAV and BDD-hFVIII.Solid line indicates hFVIII antigen level; and broken line, anti-BDD-hFVIII inhibitor titer. The ELISA standard curve for hFVIII was obtained by using pooled normal human plasma diluted in either barbital-buffered saline or mouse plasma. Values (± SEM) represent the averages of three animals.
Hengjun Chao, and Christopher E. Walsh Blood 2001;97:
©2001 by American Society of Hematology