1. Ch. 6: An Introduction to Metabolism
The chemistry of life…..

2. Metabolism Catabolic pathways Anabolic pathways
e.g. cellular respirations
Anabolic pathways
e.g. protein synthesis

3. Organisms transform energy
KE = Kinetic Energy, energy in motion
PE = Potential Energy, energy stored
energy can be transformed from one form to another

4. Laws of Thermodynamics
The first law of thermodynamics
E is neither created or destroyed
The second law of thermodynamics
Entropy
organisms live at the expense of free energy
exergonic reactions
endergonic reactions

5. Disequilibrium Cell that reaches equilibrium is dead Open System
Sequence of reactions
Coupling: use of an exergonic process to drive an endergonic one

6. Why do I have
to do all this
work!
ATP

7. ATP structure chemical reaction that results in the release of energy
How does ATP perform work? Phosphorylation Transfer
Regeneration of ATP

8. Phosphorylation of ATP

9. ATP
…that 107 molecules of ATP are used and then regenerated per second per cell?
Did you know?

10. Enzymes Speed up reaction rate: Catalyst Catalytic Protein
Activation Energy needed

11. Exergonic Reaction Enzymes lower barrier of activation energy
Does not speed up reaction. Hastens reactions that would occur normally.

12. Enzymes Active Site

13. Inhibition of Enzymes

14. The control of metabolism
regulated by controlling enzyme activity
allosteric regulation
feedback inhibition
cooperativity
location of enzymes in the cell