Presentation is loading. Please wait.

Presentation is loading. Please wait.

In Vitro Fertilization May Increase the Risk of Beckwith-Wiedemann Syndrome Related to the Abnormal Imprinting of the KCNQ1OT Gene  Christine Gicquel,

Published byEustace Emory Mitchell Modified over 6 years ago

Similar presentations

Presentation on theme: "In Vitro Fertilization May Increase the Risk of Beckwith-Wiedemann Syndrome Related to the Abnormal Imprinting of the KCNQ1OT Gene  Christine Gicquel,"— Presentation transcript:

1 In Vitro Fertilization May Increase the Risk of Beckwith-Wiedemann Syndrome Related to the Abnormal Imprinting of the KCNQ1OT Gene  Christine Gicquel, Véronique Gaston, Jacqueline Mandelbaum, Jean-Pierre Siffroi, Antoine Flahault, Yves Le Bouc  The American Journal of Human Genetics  Volume 72, Issue 5, Pages (May 2003) DOI: /374824 Copyright © 2003 The American Society of Human Genetics Terms and Conditions

2 Figure 1 Methylation analysis of KvDMR1 in liver tissue (patient 131) and leukocytes (patients 15, 94, 98, 115, and 137) from the six patients with BWS born after ART and in leukocytes from a normal control (C). Genomic DNA was digested with BamHI and the methylation-sensitive enzyme NotI. Digested samples were subjected to electrophoresis in a 0.7% agarose gel, blotted onto Hybond XL membranes, and hybridized with the HLHAY79 KvDMR1 probe corresponding to EST (ATCC; Manassas). The upper band (6 kb) is methylated and corresponds to the maternal allele. The lower band (4.2 kb) is unmethylated and corresponds to the paternal allele. The American Journal of Human Genetics  , DOI: ( /374824) Copyright © 2003 The American Society of Human Genetics Terms and Conditions

Download ppt "In Vitro Fertilization May Increase the Risk of Beckwith-Wiedemann Syndrome Related to the Abnormal Imprinting of the KCNQ1OT Gene  Christine Gicquel,"

Similar presentations

Nuclear and Mitochondrial DNA Analysis of a 2,000-Year-Old Necropolis in the Egyin Gol Valley of Mongolia Christine Keyser-Tracqui, Eric Crubézy, Bertrand.

Nuclear and Mitochondrial DNA Analysis of a 2,000-Year-Old Necropolis in the Egyin Gol Valley of Mongolia Christine Keyser-Tracqui, Eric Crubézy, Bertrand.
Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and.

Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and.
Functional Analysis of the Neurofibromatosis Type 2 Protein by Means of Disease- Causing Point Mutations Renee P. Stokowski, David R. Cox The American.

Functional Analysis of the Neurofibromatosis Type 2 Protein by Means of Disease- Causing Point Mutations Renee P. Stokowski, David R. Cox The American.
Gene Preference in Maple Syrup Urine Disease Mary M. Nellis, Dean J. Danner The American Journal of Human Genetics Volume 68, Issue 1, Pages 232-237 (January.

Gene Preference in Maple Syrup Urine Disease Mary M. Nellis, Dean J. Danner The American Journal of Human Genetics Volume 68, Issue 1, Pages (January.
Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part I: Methods and Power Analysis Douglas F. Levinson, Matthew D. Levinson, Ricardo Segurado,

Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part I: Methods and Power Analysis Douglas F. Levinson, Matthew D. Levinson, Ricardo Segurado,
Growth and development of children born after in vitro fertilization

Growth and development of children born after in vitro fertilization
Deletions of the INK4A Gene Occur in Malignant Peripheral Nerve Sheath Tumors but not in Neurofibromas  Helen P. Kourea, Irene Orlow, Bernd W. Scheithauer,

Deletions of the INK4A Gene Occur in Malignant Peripheral Nerve Sheath Tumors but not in Neurofibromas  Helen P. Kourea, Irene Orlow, Bernd W. Scheithauer,
Imprinting-Mutation Mechanisms in Prader-Willi Syndrome

Imprinting-Mutation Mechanisms in Prader-Willi Syndrome
Detection of Exon 12 Mutations in the JAK2 Gene

Detection of Exon 12 Mutations in the JAK2 Gene
A Pseudo-Full Mutation Identified in Fragile X Assay Reveals a Novel Base Change Abolishing an EcoRI Restriction Site  Shujian Liang, Harold N. Bass,

A Pseudo-Full Mutation Identified in Fragile X Assay Reveals a Novel Base Change Abolishing an EcoRI Restriction Site  Shujian Liang, Harold N. Bass,
Isothermal Multiple Displacement Amplification

Isothermal Multiple Displacement Amplification
Yanggu Shi, Sharon F. Terry, Patrick F. Terry, Lionel G

Yanggu Shi, Sharon F. Terry, Patrick F. Terry, Lionel G
Methylation-Specific Multiplex Ligation-Dependent Probe Amplification Enables a Rapid and Reliable Distinction between Male FMR1 Premutation and Full-Mutation.

Methylation-Specific Multiplex Ligation-Dependent Probe Amplification Enables a Rapid and Reliable Distinction between Male FMR1 Premutation and Full-Mutation.
Zoran Brkanac, Jannine D. Cody, Robin J. Leach, Barbara R. DuPont 

Zoran Brkanac, Jannine D. Cody, Robin J. Leach, Barbara R. DuPont 
Simultaneous Detection and Quantification of Mitochondrial DNA Deletion(s), Depletion, and Over-Replication in Patients with Mitochondrial Disease  Ren-Kui.

Simultaneous Detection and Quantification of Mitochondrial DNA Deletion(s), Depletion, and Over-Replication in Patients with Mitochondrial Disease  Ren-Kui.
Analysis of the COL1A1 and COL1A2 Genes by PCR Amplification and Scanning by Conformation-Sensitive Gel Electrophoresis Identifies Only COL1A1 Mutations.

Analysis of the COL1A1 and COL1A2 Genes by PCR Amplification and Scanning by Conformation-Sensitive Gel Electrophoresis Identifies Only COL1A1 Mutations.
162. Stability of Polymer/Plasmid DNA Complexes In Vitro and In Vivo

162. Stability of Polymer/Plasmid DNA Complexes In Vitro and In Vivo
Discordance between Genetic and Epigenetic Defects in Pseudohypoparathyroidism Type 1b Revealed by Inconsistent Loss of Maternal Imprinting at GNAS1 

Discordance between Genetic and Epigenetic Defects in Pseudohypoparathyroidism Type 1b Revealed by Inconsistent Loss of Maternal Imprinting at GNAS1 
The DMPK Gene of Severely Affected Myotonic Dystrophy Patients Is Hypermethylated Proximal to the Largely Expanded CTG Repeat  Peter Steinbach, Dieter.

The DMPK Gene of Severely Affected Myotonic Dystrophy Patients Is Hypermethylated Proximal to the Largely Expanded CTG Repeat  Peter Steinbach, Dieter.
Volume 126, Issue 4, Pages (April 2004)

Volume 126, Issue 4, Pages (April 2004)

Similar presentations

Ads by Google