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Published byΚυρία Ζαΐμης Modified over 6 years ago
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In vitro photoacoustic visualization of myocardial ablation lesions
Nicholas Dana, BSc, Luigi Di Biase, MD, PhD, FHRS, Andrea Natale, MD, FHRS, Stanislav Emelianov, PhD, Richard Bouchard, PhD Heart Rhythm Volume 11, Issue 1, Pages (January 2014) DOI: /j.hrthm Copyright © 2014 Heart Rhythm Society Terms and Conditions
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Figure 1 Schematic of combined photoacoustic/ultrasound (PA/US) imaging system. Heart Rhythm , DOI: ( /j.hrthm ) Copyright © 2014 Heart Rhythm Society Terms and Conditions
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Figure 2 A: Single-wavelength photoacoustic image (710 nm) overlaying ultrasound image with ablated and non-ablated ROIs. B: Mean ROI photoacoustic signal plotted vs wavelength. C: Tissue characterization map (TCM). D: Reference spectra for ablated (averaged over eight samples from two hearts) and non-ablated (derived from optical extinction data from deoxyhemoglobin) tissue. Heart Rhythm , DOI: ( /j.hrthm ) Copyright © 2014 Heart Rhythm Society Terms and Conditions
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Figure 3 Top-view (A) and side-view (C) stained sample gross pathology with sample boundary (blue) and ablated region (red) segmentation. Matching top-view (B) and side-view (D) TCM-US images with segmented ablated region (red). Heart Rhythm , DOI: ( /j.hrthm ) Copyright © 2014 Heart Rhythm Society Terms and Conditions
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Figure 4 Three-dimensional rendering (A) of TCM volume with clipping plane corresponding to tissue bisection (B). Matching top-view (C) and side-view (D) gross pathology photographs with axes and fields of view indicated by arrows and boxes, respectively. Heart Rhythm , DOI: ( /j.hrthm ) Copyright © 2014 Heart Rhythm Society Terms and Conditions
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