1. Volume 124, Issue 4, Pages 880-888 (April 2003)
Methylene blue-aided chromoendoscopy for the detection of intraepithelial neoplasia and colon cancer in ulcerative colitis 
Ralf Kiesslich, Johannes Fritsch, Martin Holtmann, Heinz H. Koehler, Manfred Stolte, Stephan Kanzler, Bernhard Nafe, Michael Jung, Peter R. Galle, Markus F. Neurath 
Gastroenterology 
Volume 124, Issue 4, Pages (April 2003)
DOI: /gast
Copyright © 2003 American Gastroenterological Association Terms and Conditions

2. Fig. 1
Flow diagram of the progress through the phases of the actual randomized trial according to the CONSORT statement. Data from Moher et al.20.
Gastroenterology  , DOI: ( /gast )
Copyright © 2003 American Gastroenterological Association Terms and Conditions

3. Fig. 3
(A) Within previously unremarkable colonic mucosa, a discretely elevated lesion is visible after staining (arrows). (B) On closer inspection, an irregular surface structure is visible. On histologic analysis, this lesion was identified as low-grade intraepithelial neoplasia.
Gastroenterology  , DOI: ( /gast )
Copyright © 2003 American Gastroenterological Association Terms and Conditions

4. Fig. 4
(A) The native colonic mucosa shows areas of focal erythema. (B) After CE, a flat lesion is seen that correlates with high-grade intraepithelial neoplasia on histology.
Gastroenterology  , DOI: ( /gast )
Copyright © 2003 American Gastroenterological Association Terms and Conditions

5. Fig. 5
(A) Magnification endoscopy of a superficially spreading colon cancer in UC. (B) The respective histologic findings correlate well with the endoscopic picture.
Gastroenterology  , DOI: ( /gast )
Copyright © 2003 American Gastroenterological Association Terms and Conditions

6. Fig. 2
(A) Pseudopolyp shortly after vital staining with methylene blue. The surface staining pattern has the same structure as the surrounding mucosa (pit pattern I). (B) Staining pattern of a hyperplastic polyp after absorption of methylene blue. The crypts show a stellate distribution pattern (pit pattern II). In both cases, histologic analysis showed a hyperplastic epithelium without neoplastic changes.
Gastroenterology  , DOI: ( /gast )
Copyright © 2003 American Gastroenterological Association Terms and Conditions