3. Learning Objectives

4. Current Practices in Ruling Out AMI

5. 6 Million Chest Pain Visits Evaluated Annually in the US

6. Can We Do Better?

7. 3 Clinical Evaluation Tools

8. APACE hs-cTnT 1-Hour Algorithm

9. Patient Inclusion/Exclusion Criteria

10. ED Prevalence of Acute MI

11. TRAPID-AMI Results Presented at ESC 2014

12. Clinical Implications

13. Limitations

14. Baseline Patient Characteristics

15. One Cut-off Does Not Fit All

16. Age- and Sex-Dependent Upper Reference Limits for hs-cTnT

17. Could Older Adults Be at Greater Risk of A “False Positive” Diagnosis of AMI?

18. Algorithm is Based on 2 Main Concepts

19. Key Clinical Points

20. Recap 1-Hour Algorithm With Hs-cTnT

21. Differential Between MI Types 1 and 2 According to Condition of the Coronary Arteries

22. Take-Home Points and Summary

23. Abbreviations

24. Abbreviations (cont)

25. References

26. References (cont)