1. Patent Ductus Arteriosus Occlusion Device Oral Presentation #1
Group 6
David Brogan, Darci Phillips & Daniel Schultz
Advisor: Dr. Thomas Doyle
1/15/2003

2. Patent Ductus Arteriosus (PDA)
Ductus arteriosus (DA) allows blood to bypass pulmonary and enter systemic
Usually DA closes within hrs of delivery (if not deemed abnormal/patent)
PDA occurs in 1/ live births
Many adverse effects (growth retardation, breathlessness or lack of appetite
Most common problem is congestive heart failure
1/15/2003

3. Current Treatments Drug therapy (indomethacin)
Implantable devices (most common are coils)
Usually need 3-4 coils
Difficult to remove and reposition
Invasive surgery (ligate the PDA to inhibit blood flow)
1/15/2003

4. Project Goals
To design, develop and patent a PDA occlusion device that can…
Be delivered via a catheter
Conform to the shape of the PDA and cause occlusion
Can be repositioned
Be cost effective (<$200)
Provide an initial success rate of 100%
1/15/2003

5. Our Design
1/15/2003

6. Current Status
Conducted extensive research on other treatment methods (to avoid short comings on our design)
Design refinement finalization
PDA Device prototype
Design testing apparatus
Making adjustments to website
1/15/2003

7. Needs Inquired with multiple companies about …
Biocompatible and expandable foam
Biocompatible memory wire
Have not received a response and thus are seeking assistance from a biomaterials expert
1/15/2003

8. Future Direction Build a test device for the Patent Ductus environment
Conduct strength and pressure testing
Refine design based upon testing
Build scaled prototype with correct biomaterials
Talk with Dr. Doyle about patenting this PDA Occlusion Device
1/15/2003

9. Contact Information
David Brogan
Darci Phillips
Daniel Schultz
1/15/2003