1. Genomics of epidemic pathogens
K. Georgiades 
Clinical Microbiology and Infection 
Volume 18, Issue 3, Pages (March 2012)
DOI: /j x
Copyright © 2012 European Society of Clinical Infectious Diseases Terms and Conditions

2. FIG. 1
Creation of an epidemic pathogen. Non-specialized bacterial species constitute ‘pre-species’ that have a community lifestyle and are able to exchange genes. After specialization, the number of horizontal gene transfers (HGTs) is reduced, until total genetic isolation has been acheived. Only gene loss is then possible, the bacterium is deregulated, and virulence capacity is initiated. The arrows show HGT and gene loss. TA, toxin–antitoxin.
Clinical Microbiology and Infection  , DOI: ( /j x)
Copyright © 2012 European Society of Clinical Infectious Diseases Terms and Conditions