1. Hardy –Weinberg Investigation 2
Battling Beetles- Lab Journal

2. Worksheet 1 3. q=.2; p=.8, 2pq=.32 4. 46.8%, p2= .14 5. q2=0.0025
8. homozygous dominant individuals= 125, hetrozygous individuals= 250
9. homozygous dominant (straight thumb)=90, heterozygous (straight thumb)= 420, Hitchiker’s thumb= 490

3. Think….Write… Think about the term Natural selection
Write down as many terms as you associate with this term
You have 2 minutes go

4. Teams of 3 Assign the following roles
Analyzer- will examine the 3 lists and highlight common terms
Recorder- compiles 2 lists one of shared terms and one of unique terms (these are terms that might be shared by 2 of the team but not all 30
Reporter- will after group discussion report to the class the 2 terms that the group should be included on a group list of terms related to Natural selection

5. Discuss which of these cartoon characters provides best explanation and why.

6. OPENER What is evolution?
What are the basic principles of evolution by natural selection?
Are there other mechanisms of evolution? If so, (hint there are) describe them.

7. Scenario 1- Ideal model Generation AA Aa aa 1 18 2 5 7 6 3 12 4 10 9 818 2 5 7 6 3 12 4 10 9 8
Calculate the new p and q values at the end of Generation 7.
Is this population evolving? Justify your response.

8. Scenario 2- Selection model
Generation AA Aa aa 1 18 2 4 14 3 5 13 6 12 7
Calculate the new p and q values at the end of Generation 7.
Is this population evolving? Justify your response.

9. Scenario 3- Small populations model
Generation AA Aa aa 1 8 2 4 3 5
Generation AA Aa aa 1 10 2 5 3 7 4
Calculate the new p and q values at the end of Generation 5 for each population.
Is this population evolving? Justify your response.

10. Opener
In humans, unattached earlobes are dominant, and attached earlobes are recessive. In China, it is reported that 64% of the population exhibit unattached earlobes.
Question A: What percentage of the Chinese population exhibit attached earlobes?
Question B: What is the frequency of the recessive (attached earlobe) allele in the Chinese population?
Question C: What is the frequency of the dominant (unattached earlobe) allele in the Chinese population?
Question D: What percentage of the Chinese population are homozygous for the dominant allele (unattached earlobe)?
Question E: What percentage of the Chinese population are heterozygous for the earlobe allele?

11. Scenario 4- Sexual Selection Model
Generation AA Aa aa 1 18 2 3 4 5 6 7
Calculate the new p and q values at the end of Generation 7.
Is this population evolving? Justify your response.

12. Now let’s go back and examine the consequences of each scenario
Is there a change in the allelic frequencies?
Is evolution occurring
Model 1 –
Model 2
Model 3
Model 4

13. Mathematical Modeling: Hardy -Weinberg
Complete Part 1- Battling Beetles
Watch this video
Part 2 – the Heterozygous Advantage – Malaria and Sickle Cell
Part 3 – Class activity- mathematical modeling of HW and what happens when we manipulate or violate the 5 conditions
Part 4 – Using Excel to model H-W and populations.

14. Creating a Lab Journal
The purpose of a lab journal is to keep a complete record of all lab activities in this class.