1. Gerhard Heinemeyer Herbert Desel Joanna Tempowski
Toxicological Documentation & Information Network A European Challenge? Results from a Workshop, September 2002, Berlin
Gerhard Heinemeyer
Herbert Desel
Joanna Tempowski

2. Improvement of Knowledge
Improving Quality =
Improvement of Knowledge

3. What is TDI? Toxicological Documentation and Information
Project of research and development
Participants:
7 German poison centres (active, developers)
3 Poison centres (passive, received software etc.)
BfR*) (scientific consultant, development)
Objective: To develop standard software tools for exchange of data from industry to poison centres and BgVV/BfR
Products, substances, cases
Running since 1999
*) Federal Institute for Risk Assessment, former BgVV

4. Project TDI (I)
Aim: To improve knowledge about product composition by electronic exchange of formulation data between industry, authorities and poison centres in Germany
Approach: To install a common structure for data exchange between industry, poison centres, and national authorities

5. TDI (II) - Results
Implementation of a standardised data exchange format
Databank TDI
Aggreement upon standard procedures
Extension to XML-format
European Impact?
for centres and agencies
for industry

6. Presentation of results (TDI-Workshop Sept. 2002)
To inform about TDI and present results
To discuss results and possible consequences
To give an overview on the current situation in Europe
To discuss the impact of collaboration with industry and among poison centres on an international basis.

7. Questions? TDI-workshop
Are there similar approaches elsewhere?
Can experiences from this study be transferred to Europe?
What is the role of EU, EAPCCT and others (WHO)?
Round table was held to discuss benefits and possible problems!

8. Results from Round Table (I)
TDI-workshop
Increase knowledge on frequency and severity of poisoning
Interested parties for this exchange may be represented by:
Poison centres (can more readily share information about cases)
Industry (is informed about safety of products)
Regulators (data to support priority setting for chemical evaluations and better information about toxic effects in humans)

9. Results from Round Table (II)
TDI-workshop
Distribution of product information on the basis of accepted standards (standardised formats and standardised protocols)
Same level of information for all PC's
Product information will be more readily accessible, particularly where products are marketed in several countries (Industry doesn't want to have multiple partners)
Linkage of product and case documentation
Improvement of risk assessment approaches

10. Requirements TDI-Workshop
Intention
Each partner (poison centres, industry, regulators, and others) must have the intention and commitment to become involved in a system of data exchange
Standardised formats
Agreement for the data elements to be exchanged
Use of the XML language should be given reference

11. Future work TDI-workshop
start co-operation
this minisymposium
Establish an electronic discussion forum
Standardize terms (e.g. substances)
BfR provides a list of substances terms and synonyms
EAPCCT initiative for improvement of product information exchange
WHO initiative
update of standardised formats for case data and definitions of data elements (contributions of L. Onyon and J. Tempowski, this meeting)

12. This mini-symposium? EAPCCT initiative
discuss the impact of using standard data by electronic exchange
specific opinions regarding the role of the EAPCCT?
Focus on product information and their electronic dissimination
Approvement by EAPCCT and publication?
other objectives, recommendations?

13. Aims, objectives to be discussed today?
Do PC‘s see similar benefits?
Prerequesites
Recommendations?
Standardised data exchange format for European industry, poison centres and agencies
Should EAPCCT have a lead function as proposed by the workshop and which are the consequences?
Punkte, die bei diskutiert werden sollen

14. This minisysmposium:
four lecturs about data exchange
45 minute discussion
recommendations how to proceed?