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Heparin, urokinase, and ancrod alter neutrophil function

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Presentation on theme: "Heparin, urokinase, and ancrod alter neutrophil function"— Presentation transcript:

1 Heparin, urokinase, and ancrod alter neutrophil function
Julie A. Freischlag, MD, Michael D. Colburn, MD, William J. Quiñones-Baldrich, MD, Wesley S. Moore, MD  Journal of Vascular Surgery  Volume 16, Issue 4, Pages (October 1992) DOI: / (92) Copyright © 1992 Society for Vascular Surgery and the North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

2 Fig. 1 Chart shows effect of tested doses of each agent on production of superoxide anion by activated human PMNs at concentration of 2 × 106 cells/ml. Journal of Vascular Surgery  , DOI: ( / (92) ) Copyright © 1992 Society for Vascular Surgery and the North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

3 Fig. 2 Chart shows effect of tested doses of each agent on chemotaxis of human PMNs at a concentration of 2 × 106 cells/ml. Serum from corresponding subject for each experiment was used as chemoattractant. Asterisks denote statistical significance (p < 0.01) compared with control. Journal of Vascular Surgery  , DOI: ( / (92) ) Copyright © 1992 Society for Vascular Surgery and the North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

4 Fig. 3 Chart shows effect of tested doses of each agent on phagocytosis of opsonized zymosan by human PMNs at concentration of 2 × 106 cells/ml. Serum from corresponding subject for each experiment was used to opsonize zymosan particles. Asterisks denote statistical significance (*p < 0.01; **p < 0.05) compared with control. Journal of Vascular Surgery  , DOI: ( / (92) ) Copyright © 1992 Society for Vascular Surgery and the North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions


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