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Volume 57, Issue 3, Pages (March 2010)

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1 Volume 57, Issue 3, Pages 522-529 (March 2010)
Effects of Phosphodiesterase Inhibitors on the Inflammatory Response of Endothelial Cells Stimulated by Myeloperoxidase-Modified Low-Density Lipoprotein or Tumor Necrosis Factor Alpha  Thierry Roumeguère, Karim Zouaoui Boudjeltia, Sajida Babar, Vincent Nuyens, Alexandre Rousseau, Pierre Van Antwerpen, Jean Ducobu, Eric Wespes, Michel Vanhaeverbeek  European Urology  Volume 57, Issue 3, Pages (March 2010) DOI: /j.eururo Copyright © 2009 European Association of Urology Terms and Conditions

2 Fig. 1 Interleukin 8 (IL-8) production by endothelial cells with native low-density lipoprotein (LDL), with myeloperoxidase-modified LDL (Mox-LDL), and with tumor necrosis factor alpha (TNF-α) alone. n=at least three times (ie, in triplicate). European Urology  , DOI: ( /j.eururo ) Copyright © 2009 European Association of Urology Terms and Conditions

3 Fig. 2 Interleukin 8 (IL-8) production by endothelial cells with myeloperoxidase-modified low-density lipoprotein (Mox-LDL) alone, with sildenafil (1μM, 5μM, and 10μM) alone, or with sildenafil (1μM, 5μM, and 10μM) with Mox-LDL. European Urology  , DOI: ( /j.eururo ) Copyright © 2009 European Association of Urology Terms and Conditions

4 Fig. 3 Interleukin 8 (IL-8) production by endothelial cells with tumor necrosis factor alpha (TNF-α) alone or with sildenafil (1μM, 5μM, and 10μM) plus TNF-α. European Urology  , DOI: ( /j.eururo ) Copyright © 2009 European Association of Urology Terms and Conditions

5 Fig. 4 Interleukin 8 (IL-8) production by endothelial cells with myeloperoxidase-modified low-density lipoprotein (Mox-LDL) alone, with vardenafil (1μM, 5μM, and 10μM) alone, or with vardenafil (1μM, 5μM, and 10μM) with Mox-LDL. European Urology  , DOI: ( /j.eururo ) Copyright © 2009 European Association of Urology Terms and Conditions

6 Fig. 5 Interleukin 8 (IL-8) production by endothelial cells with tumor necrosis factor alpha (TNF-α) alone or with vardenafil (1μM, 5μM, and 10μM) plus TNF-α. European Urology  , DOI: ( /j.eururo ) Copyright © 2009 European Association of Urology Terms and Conditions

7 Fig. 6 Interleukin 8 (IL-8) production by endothelial cells with myeloperoxidase-modified low-density lipoprotein (Mox-LDL) alone, with tadalafil (1μM and 3μM) alone, or with tadalafil (1μM and 3μM) plus Mox-LDL. European Urology  , DOI: ( /j.eururo ) Copyright © 2009 European Association of Urology Terms and Conditions

8 Fig. 7 Interleukin 8 (IL-8) production by endothelial cells with tumor necrosis factor alpha (TNF-α) alone or with tadalafil (1μM and 3μM) plus TNF-α. European Urology  , DOI: ( /j.eururo ) Copyright © 2009 European Association of Urology Terms and Conditions


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