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The DNA Damage Response: Ten Years After

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1 The DNA Damage Response: Ten Years After
J. Wade Harper, Stephen J. Elledge  Molecular Cell  Volume 28, Issue 5, Pages (December 2007) DOI: /j.molcel Copyright © 2007 Elsevier Inc. Terms and Conditions

2 Figure 1 The DNA Damage Response Then and Now
A schematic of the DDRs discussed in this perspective. The red x's represent replication blocks, and the red arrows indicate the direction of movement of replication helicases and polymerases. Open circles containing “P” represent phosphate, while green filled circles represent ubiquitin. Molecular Cell  , DOI: ( /j.molcel ) Copyright © 2007 Elsevier Inc. Terms and Conditions

3 Figure 2 Biochemical and Physiological Consequences of the DNA Damage Response Molecular Cell  , DOI: ( /j.molcel ) Copyright © 2007 Elsevier Inc. Terms and Conditions

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