Download presentation
Presentation is loading. Please wait.
1
Volume 19, Issue 2, Pages 121-130 (April 2012)
Lycopene attenuates oxidative stress and heart lysosomal damage in isoproterenol induced cardiotoxicity in rats: A biochemical study Ahmed M. Mohamadin, Ahmed A. Elberry, Amr D. Mariee, Gehan M. Morsy, Fahad A. Al-Abbasi Pathophysiology Volume 19, Issue 2, Pages (April 2012) DOI: /j.pathophys Copyright © 2012 Elsevier Ireland Ltd Terms and Conditions
2
Fig. 1 Effect of lycopene (LYC) on the activity of cardiac marker enzymes in the serum of control and isoproterenol (ISO)-induced oxidative stress and cardiotoxicity in rats. Values are the mean±SEM for 12 animals in each group. ap<0.01 compared with the control group, bp<0.01 compared with the ISO group, cp<0.01 compared with the LYC+ISO group. Pathophysiology , DOI: ( /j.pathophys ) Copyright © 2012 Elsevier Ireland Ltd Terms and Conditions
3
Fig. 2 Effect of lycopene (LYC) on the level of cardiac oxidative stress markers (A) GSH, (B) TBARS and (C) PCC in control and isoproterenol-(ISO) induced oxidative stress and cardiotoxicity in rats. Values are the mean±SEM for 12 animals in each group. ap<0.01 compared with the control group, bp<0.01 compared with the ISO group, cp<0.01 compared with the LYC+ISO group. Pathophysiology , DOI: ( /j.pathophys ) Copyright © 2012 Elsevier Ireland Ltd Terms and Conditions
4
Fig. 3 Effect of lycopene (LYC) on the level of serum antioxidants (A) GSH and (B) vitamin C in control and isoproterenol (ISO)-induced oxidative stress and cardiotoxicity in rats. Values are the mean±SEM for 12 animals in each group. ap<0.01 compared with the control group, bp<0.01 compared with the ISO group, cp<0.01 compared with the LYC+ISO group. Pathophysiology , DOI: ( /j.pathophys ) Copyright © 2012 Elsevier Ireland Ltd Terms and Conditions
5
Fig. 4 Effect of lycopene (LYC) on the activities of heart enzymatic antioxidants (A) SOD, (B) CAT and (C) GSH-Px in control and isoproterenol (ISO)-induced oxidative stress and cardiotoxicity in rats. Values are the mean±SEM for 12 animals in each group. ap<0.01 compared with the control group, bp<0.01 compared with the ISO group, cp<0.01 compared with the LYC+ISO group. Pathophysiology , DOI: ( /j.pathophys ) Copyright © 2012 Elsevier Ireland Ltd Terms and Conditions
6
Fig. 5 Effect of lycopene (LYC) on cardiac myeloperoxidase (MPO) activity in control and isoproterenol-(ISO) induced oxidative stress and cardiotoxicity in rats. Values are the mean±SEM for 12 animals in each group. ap<0.01 compared with the control group, bp<0.01 compared with the ISO group, cp<0.01 compared with the LYC+ISO group. Pathophysiology , DOI: ( /j.pathophys ) Copyright © 2012 Elsevier Ireland Ltd Terms and Conditions
7
Fig. 6 In vitro scavenging effect of lycopene on 2,2′-azinobis-(3-ethyl-benzothiazoline-6-sulfonic acid) radical (total antioxidant assay). Pathophysiology , DOI: ( /j.pathophys ) Copyright © 2012 Elsevier Ireland Ltd Terms and Conditions
Similar presentations
© 2025 SlidePlayer.com. Inc.
All rights reserved.