1. Optimization of opioid therapy for preventing incident pain associated with bone metastases 
Sebastiano Mercadante, MD, Patrizia Villari, MD, Patrizia Ferrera, MD, Alessandra Casuccio, BS 
Journal of Pain and Symptom Management 
Volume 28, Issue 5, Pages (November 2004)
DOI: /j.jpainsymman
Copyright © 2004 U.S. Cancer Pain Relief Committee Terms and Conditions

2. Fig. 1 Construct for opioid titration in incident pain.
Journal of Pain and Symptom Management  , DOI: ( /j.jpainsymman )
Copyright © 2004 U.S. Cancer Pain Relief Committee Terms and Conditions

3. Fig. 2
Example of pain intensity (at rest and with movement) at admission (a), one day after achieving basal pain control, less than 4/10 (b), after optimizing opioid doses (c).
Journal of Pain and Symptom Management  , DOI: ( /j.jpainsymman )
Copyright © 2004 U.S. Cancer Pain Relief Committee Terms and Conditions