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Robert Koch: The Grandfather of Cloning?

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Presentation on theme: "Robert Koch: The Grandfather of Cloning?"— Presentation transcript:

1 Robert Koch: The Grandfather of Cloning?
Robin A. Weiss  Cell  Volume 123, Issue 4, Pages (November 2005) DOI: /j.cell Copyright © 2005 Elsevier Inc. Terms and Conditions

2 Figure 1 Robert Koch in 1884 (Courtesy of the Robert Koch Institute)
Cell  , DOI: ( /j.cell ) Copyright © 2005 Elsevier Inc. Terms and Conditions

3 Figure 2 Clones that Koch Would Recognize
(A) Colonies of E. coli on agar in a Petri dish. White clones contain recombinant DNA, whereas blue clones are wild-type (S. Nambulli and I. Harrison, Wohl Virion Centre). (B) Polio virus plaques in a monolayer of HeLa cells under agar (courtesy of J.E. Darnell, Jr). (C) Rous sarcoma virus assay on a monolayer of quail embryo fibroblasts and (D) scanning electron micrograph of a transformed clone (R.A. Weiss, 1969, PhD thesis, University of London). (E) Cloning of human HeLa cells by T.T. Puck, P.I. Marcus, and S.J. Cieciura and (F) individual clone showing epithelial morphology (reproduced from The Journal of Experimental Medicine (1956). 103, 273–283 by copyright permission of the Rockefeller University Press). Cell  , DOI: ( /j.cell ) Copyright © 2005 Elsevier Inc. Terms and Conditions

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