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Searching the NCBI Databases
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Search for CFTR[gene] in the Protein database
What is it?
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Limit to genes in human only CFTR[gene] AND human[orgn]
How many?
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Restrict to RefSeq How many?
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RefSeq records can also be filtered using the Limits tab
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Examine the NP_000483 record How many amino-acids are in the protein?
On which chromosome is this protein-coding gene located?
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Follow the dbSNP link to examine the SNPs associated with this protein
How many SNPs?
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Follow the dbSNP link to examine the SNPs associated with this protein
Describe mutation in first record. Is it synonymous?
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Use the Taxonomy Browser to examine fully-sequenced primates genomes
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Use the Taxonomy Browser to examine fully-sequenced prototheria genomes
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Sequence Retrieval
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Search for human BRCA1 in Protein database
Select longest isoform
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Display the sequences in FASTA format
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Save the sequence into a WORD file
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