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Localized Malignant Pleural Mesothelioma: Report of Two Cases

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1 Localized Malignant Pleural Mesothelioma: Report of Two Cases
Silvia Tanzi, MD, Marcello Tiseo, MD, Eveline Internullo, MD, Giancarlo Cacciani, MD, Roberto Capra, MD, Paolo Carbognani, MD, Michele Rusca, MD, Guido Rindi, MD, PhD, Andrea Ardizzoni, MD  Journal of Thoracic Oncology  Volume 4, Issue 8, Pages (August 2009) DOI: /JTO.0b013e3181a8c874 Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 A, Histology (hematoxylin-eosin staining) of localized pleural mesothelioma of mixed (sarcomatoid and epithelial) type with initial bone and pulmonary infiltration; the spectrum of microscopic findings shows several nodules partially necrotic onto desmoplastic stroma; B, sarcomatoid component. Journal of Thoracic Oncology 2009 4, DOI: ( /JTO.0b013e3181a8c874) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Thoracic computerized tomography (CT) shows a pleural mass with smooth margins and without ribs infiltration in the superior lobe of the right lung. Journal of Thoracic Oncology 2009 4, DOI: ( /JTO.0b013e3181a8c874) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 Thoracic computerized tomography (CT) shows a lobulated pleural mass with smooth margins and without ribs infiltration in the apex of the pleural cavity. Journal of Thoracic Oncology 2009 4, DOI: ( /JTO.0b013e3181a8c874) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

5 FIGURE 4 A, Histology (hematoxylin-eosin staining) of localized pleural mesothelioma of sarcomatoid type, lympho-histiocitoid variant. The neoplastic lesion shows a solid structure, inflammatory infiltration and focal necrosis; B, intermediate-large fusiform cells with abundant cytoplasm and severe cytologic atypia with frequent atypical mitoses. Journal of Thoracic Oncology 2009 4, DOI: ( /JTO.0b013e3181a8c874) Copyright © 2009 International Association for the Study of Lung Cancer Terms and Conditions

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